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Lactobacillus Casei – Inhibits the inflammatory response
Lactobacillus Casei is a species of bacteria that belongs to the genus Lactobacillus. This particular bacterium has a wide temperature and pH range. It produces the enzyme amylase. It is a very important enzyme that helps in the digestion of carbohydrates.
This bacterium is used in dairy products. Casei helps in the ripening of cheddar cheese and it is also present in fermented Silican green olives.
Lactobacillus Casei is a non-pathogenic bacterium that is among the good bacteria present in the intestinal and the digestive system. It has a lot of beneficial effects on the body. Casei protects the human body from several diseases.
It does so by restricting or inhibiting the growth of many kinds of bacteria which are potentially harmful and can cause diseases. World Health Organization of the UN stated that microorganisms like probiotics are very important and they must be administered in sufficient quantities.
How Lactobacillus Casei inhibits anti-inflammatory diseases
Lactobacillus Casei is one among the lactic acid bacteria. It produces lactic acid, which helps in a number of ways. Lactic acid helps in killing the pathogens and the bad bacteria that invade through the intestinal system and affect it.
Thus, lactic acid keeps the bad bacteria away. Another benefit of lactic acid in the digestive tract is to maintain a healthy balance of the acids and bases. If the gut reaches a highly alkaline state, then a lot of harmful organisms like Candida can overgrow. They reduce the overgrowth of such microbes; a sufficient amount of acid is required.
This acidic level and the pH balance in the gut is maintained by probiotics such as Lactobacillus Casei bacteria. Lactobacillus Casei is found naturally in the small and big intestines and the mouth of a human being. Lactobacillus Casei can also be found in dairy products like cheese, yogurt, and fermented green olives.
One strain of Casei has been found out that can decrease the inflammatory effects of Crohn’s disease. Crohn’s disease is a disease that affects the GI tract. The symptoms of this disease include weight loss, abdominal pain, diarrhea, vomiting and abdominal discomfort.
When a person is affected by this disease, the white blood cells are sent by the body to the lining of the small and large intestines that cause chronic inflammation. It eventually leads to bowel injury or ulcerations.
Other benefits of Lactobacillus Casei
Shigella is a bacterium that enters the intestine and causes dysentery and other diseases in infants and young children. Bacteria like Casei live mutually with the intestinal mucosa which contributes to the intestinal flora’s growth.
Probiotics like Lactobacillus Casei regulate the mucosal innate responses and possess anti-inflammatory properties. In a study, an analysis was made on Lactobacillus Casei and it was observed whether Casei can attenuate pro-inflammatory signaling which was caused by Shigella flexneri.
The epithelial cells were affected by Lactobacillus Casei. On further observation and examination, it was found out that Casei had reduced the number of factors responsible for the inflammation. These bacteria have developed a way to maintain the intestinal homeostasis through a method which requires the manipulation of the pathway of I-kBα.
Lactobacillus Casei is a bacterium that helps in inhibiting the anti-inflammatory response. It promotes the immune system. The bacteria reduce the creation of TNF-α from the inflated ileum of a patient suffering from Crohn’s disease.
Lactobacillus Casei bacteria contribute its anti-inflammatory properties that increase the production of anti-inflammatory cytokine IL-10. It helps in maintaining the acidic levels of the gastrointestinal tract and reduces the overgrowth of pathogens in the intestinal system. Its anti-inflammatory properties can help in the treatment of Crohn’s disease.